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产品目录

重组小鼠B7-H4(VTCN1)图片
产品货号:
JN1616
中文名称:
重组小鼠B7-H4(VTCN1)
英文名称:
Recombinant Mouse B7 Homolog 4
产品规格:
10μg|50μg|500μg|1mg
发货周期:
1~3天
产品价格:
询价
本品由我们的哺乳动物细胞表达系统制备而成,目的基因编码的Leu25-Ser256在C端带有Fc标签。

B7-H4/VTCN1质量控制:>95%(还原性SDS-PAGE)

B7-H4/VTCN1制剂:冻干品

B7-H4/VTCN1保存
冻干蛋白置于-20℃以下可长期保存,室温条件下可稳定保存3周。
复溶蛋白溶液可在4~7℃保存2~7天,可分装后置于-20℃保存三个月。

B7-H4/VTCN1复溶
打开试剂管前请先离心。
复溶浓度推荐大于100 μg/ml。
冻干蛋白请溶于ddH2O。
复溶后,请根据用量分装冻存,避免反复冻融。

关于B7-H4/VTCN1
Mouse V-set domain-containing T-cell activation inhibitor 1/VTCN1/B7-H4 is glycosylated member of the B7 family of immune co‑stimulatory proteins. B7-H4 consists of extracellular domain (ECD) with one Ig-like V-set domain and one Ig-like C2-set domain. It is widely expressed, including in kidney, liver, lung, pancreas, placenta, prostate, spleen, testis and thymus. B7-H4 negatively regulates T-cell-mediated immune response by inhibiting T-cell activation, proliferation, cytokine production and development of cytotoxicity. When expressed on the cell surface of tumor macrophages, plays an important role, together with regulatory T-cells (Treg), in the suppression of tumor-associated antigen-specific T-cell immunity. It also involved in promoting epithelial cell transformation.
相关搜索:重组小鼠B7-H4(VTCN1)Recombinant Mouse B7 Homolog 4
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